It contributes to overall better design and allows designers to focus more of their efforts on solving the specific challenges relating to a particular site and context.
The facility needed to represent best practice in GMP (good manufacturing practice) and digital automation while remaining cost effective to build and operate.. Bryden Wood was engaged to review and optimise a previously developed concept design for the site’s dry processing (milling and sieving) building.We worked closely with client stakeholders to analyse the root process requirements, identify over-provisions in the proposed design, and consolidate production onto less equipment.. Capturing these root requirements in 3D digital models called.
“Chips” (sets of interacting components.allowed us to rapidly evaluate a wide range of configuration options with client stakeholders engaged every step of the way..The reduced equipment requirements allowed us to pivot away from the originally proposed central spine corridor towards a simpler configuration of process rooms with perimeter circulation on both sides.
This, coupled with extensive deployment of glazing, allowed us to bring natural light to both circulation and process areas, enhancing the workplace environment and employee wellbeing.. Our alternative design for the milling building reduced operational CO. 2. emissions by more than 50% and capital cost by 30%.It was adopted by Pfizer and incorporated into the delivered scheme.
“The layout, space and light in the milling building is superb,” said Pfizer’s Senior Director of Operations..
The Singapore API plant is the 2024 FOYA Category Winner for Operations, Project Execution.Although not without issues, there was a strong sense that further conversations between manufacturers and the waste management industry to create new productive circular economies would be fruitful.. Strategy co-development to identify supplies of new solvents to support growing technologies – and growth in shared geographies – could foster new, efficient, and sustainable solvent supply and recycling routes.. Techno-economic modelling is seen as a vital component in guiding short-, medium and longer-term decision making on solvents.. As the chemical market changes alongside fiscal policies, understanding how to stay cost-effective and adaptable will be important.
If this kind of analysis, or at least the insights from it, could be shared widely with the industry it could help accelerate interest and action, particularly in the generics ecosystem..Problem solving in the room.
Prompted by a thought that many players in this arena are waiting for engineering for technical solutions, there was a conversation about the complexity of the problem..This is a multimodal problem to solve; even though we had suppliers, manufacturers, laboratories, regulators, waste management, academia and design engineers in the room, we accepted not everybody was represented who needs to be.
(Editor: Mini Umbrellas)